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Amlodipine Besylate; Benazepril Hydrochloride



About Amlodipine Besylate; Benazepril Hydrochloride

Benazepril Hydrochloride 40 mg and Amlodipine Besylate is a combination of two drugs a calcium channel blocker (amlodipine) and an ACE inhibitor (benazepril). Amlodipine Besylate is used to treat high blood pressure. Lotrel works by relaxing blood vessels so that blood can flow more easily. Amlodipine Besylate 5mg Lowers high blood pressure helps prevent strokes, heart attacks, and kidney problems. Generic Lotrel can be used by itself or with other medicines to treat these conditions.

How to use

Read the Patient Information Leaflet if available from your pharmacist before you start taking Amlodipine Besylate. If you have any questions, ask your doctor or pharmacist.

  • Take Lotrel by mouth with or without food as directed by your doctor
  • usually once daily.
  • Generic Lotrel dosage is based on your medical condition and response to treatment.
  • Use generic Lotrel regularly in order to get the most benefit from it.
  • To help you remember, take it at the same time each day.

Keep taking Benazepril Hydrochloride 40 mg even if you feel well. Most people with high blood pressure do not feel sick.

It may take 1 to 2 weeks before you get the full benefit of generic Lotrel. Tell your doctor if your condition does not get better or if it gets worse (your blood pressure readings remain high or increase).

Side effects

  • Dizziness
  • light-headedness
  • Dry cough
  • swelling hands/ankles/feet

If any of these Amlodipine Besylate effects last or get worse, tell your doctor or pharmacist promptly.

To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

Remember that your doctor has prescribed Benazepril Hydrochloride 40 mg because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using Lotrel do not have serious side effects.

Tell your doctor right away if any of these generic Lotrel side effects occur:

  • fainting
  • fast/irregular/pounding heartbeat
  • symptoms of a high potassium blood level
  • signs of kidney problems
Some serious and rare side effects

Amlodipine Besylate 5mg may rarely cause serious (possibly fatal) liver disease. Get medical help right away if you have any symptoms of liver damage, including

  • nausea/vomiting that doesn’t stop
  • loss of appetite
  • stomach/abdominal pain
  • yellowing eyes/skin
  • dark urine

Some people who already have severe heart disease may rarely develop worsening chest pain or a heart attack after starting Benazepril Hydrochloride 40 mg or increasing the dose. Get medical help right away if you experience: worsening chest pain, symptoms of a heart attack (such as chest/jaw/left arm pain, shortness of breath, unusual sweating).

A very serious allergic reaction to Lotrel is rare. However, get medical help right away.

Warnings & Precautions

  1. Before taking Amlodipine Besylate, tell your doctor or pharmacist if you are allergic to amlodipine or benazepril.
  2. Before using Amlodipine Besylate 5mg, tell your doctor or pharmacist your medical history.
  3. o not drive, use machinery, or do anything that needs alertness until you can do it safely.
  4. Limit alcoholic beverages.
  5. Before having surgery, tell your doctor or dentist about all the products you use.

Too much sweating, diarrhea, or vomiting may cause loss of too much body water (dehydration) and increase your risk of lightheadedness. Report prolonged diarrhea or vomiting to your doctor. Be sure to drink enough fluids to prevent dehydration unless your doctor directs you otherwise.

Amlodipine Besylate may increase your potassium levels. Before using potassium supplements or salt substitutes that contain potassium, consult your doctor or pharmacist.

Older adults may be more sensitive to the side effects of Amlodipine Besylate 5mg, including dizziness, increases in potassium level, and changes in the amount of urine (kidney problems).

Amlodipine Besylate 5mg is not recommended for use during pregnancy. Lotrel may harm an unborn baby. Consult your doctor for more details. (See also Warning section.) Benazepril Hydrochloride 40 mg passes into breast milk. Consult your doctor before breastfeeding.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Drug interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

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2.5-10 mg, 5-10 mg, 5-20 mg, 5-40 mg, 10-20 mg, 10-40 mg



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