About Insulin Isophane
Insulin Isophane Suspension is used with a proper diet and exercise program to control high blood sugar in people with diabetes. Regular and NPH insulin peak controls high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Insulin Isophane and regular take proper control of diabetes and also lessen your risk of a heart attack or stroke.
This man-made insulin product is the same as human insulin. It replaces the insulin that your body would normally make. Insulin Isophane is intermediate-acting insulin (isophane). It starts to work more slowly but lasts longer than regular insulin. Insulin isophane works by helping blood sugar (glucose) get into cells so your body can use it for energy. Insulin isophane is often used in combination with shorter-acting insulin. It may also be used alone or with other oral diabetes drugs (such as metformin).
How to use
Read the Patient Information Leaflet provided by your pharmacist before you start using Insulin Isophane Suspension and each time you get a refill. If you have any questions, ask your doctor, diabetes educator, or pharmacist.
Learn all preparation and usage instructions from your health care professional and the product package.
- Before using Regular and NPH insulin peak, gently roll the vial or cartridge, turning it upside down and right side up 10 times to mix the medication
- . Do not shake the container.
- Check Insulin Isophane and regular visually for particles or discoloration. If either is present, do not use the insulin.
- Insulin isophane should look evenly cloudy/milky after mixing.
- Do not use if you see clumps of white material, a “frosty” appearance, or particles stuck to the sides of the vial or cartridge.
Before injecting the dose
- Before injecting each dose, clean the injection site with rubbing alcohol.
- Change where you inject each time to lessen the risk of problems or damage under the skin (for example, pits/lumps or thickened skin).
- Inject this medication under the skin as directed by your doctor, usually once or twice a day.
- Do not rub the area after the injection.
- This insulin product may be injected into the stomach area, the thigh, the buttocks, or the back of the upper arm.
- Do not inject into a vein or muscle because very low blood sugar (hypoglycemia) may occur.
- Do not inject into skin that is red, swollen, itchy, or damaged.
Insulin Isophane Suspension may be mixed only with certain other insulin products such as insulin regular. Always draw the insulin regular into the syringe first, then follow with the longer-acting insulin. Never inject a mixture of different insulins into a vein. Consult your health care professional about which products may be mixed, the proper method for mixing insulin, and the proper way to inject mixtures of insulin. Do not mix insulins if you are using an insulin pump.
Don’t switch the brand
Do not change brands or types of insulin without directions on how to do so from your doctor.
Do not share your pen device with another person, even if the needle is changed. You may give other people a serious infection, or get a serious infection from them. Learn how to store and discard medical supplies safely.
Insulin Isophane Suspension dosage is based on your medical condition and response to treatment. Measure each dose very carefully because even small changes in the amount of insulin may have a large effect on your blood sugar.
Check your blood sugar regularly as directed by your doctor. Keep track of your results and share them with your doctor. This is very important in order to determine the correct insulin dose.
Use Regular and NPH insulin peak regularly to get the most benefit from it. To help you remember, use it at the same time each day.
Tell your doctor if your condition does not improve or if it worsens (your blood sugar is too high or too low).
Injection site reactions (such as pain, redness, irritation) may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed Regular and NPH insulin peak because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any serious side effects, including signs of low potassium level in the blood (such as muscle cramps, weakness, irregular heartbeat).
Insulin Isophane and regular can cause low blood sugar (hypoglycemia). This may occur if you do not consume enough calories from food or if you do unusually heavy exercise. Symptoms of low blood sugar include
- sudden sweating
- fast heartbeat
- blurred vision
- tingling hands/feet
It is a good habit to carry glucose tablets or gel to treat low blood sugar. If you don’t have these reliable forms of glucose, rapidly raise your blood sugar by eating a quick source of sugar such as table sugar, honey, or candy, or drinking fruit juice or non-diet soda. Tell your doctor right away about the reaction and the use of this product. To help prevent low blood sugar, eat meals on a regular schedule, and do not skip meals. Check with your doctor or pharmacist to find out what you should do if you miss a meal.
Symptoms of high blood sugar (hyperglycemia) include thirst, increased urination, confusion, drowsiness, flushing, rapid breathing, and fruity breath odor. If these symptoms occur, tell your doctor right away. Your dosage may need to be increased.
A very serious allergic reaction to Insulin Isophane and regular is rare. However, get medical help right away.
Warnings & Precautions
- Before using Insulin Isophane Suspension, tell your doctor or pharmacist if you are allergic to it.
- Do not use Regular and NPH insulin peak when you have low blood sugar (hypoglycemia).
- Before using this medication, tell your doctor or pharmacist your medical history.
- Do not drive, use machinery, or do any activity that requires alertness.
- Limit alcohol while using this medication.
- Before having surgery, tell your doctor or dentist about all the products you use.
It may be harder to control your blood sugar when your body is stressed (such as due to fever, infection, injury, or surgery). Consult your doctor because this may require a change in your treatment plan, medications, or blood sugar testing.
Check your blood sugar before and after exercise. You may need a snack before exercising.
If traveling across time zones, ask your doctor about how to adjust your insulin schedule. Take extra insulin and supplies with you.
Older adults may be more sensitive to the side effects of Insulin Isophane and regular, especially low blood sugar.
Children may be more sensitive to the side effects of this drug, especially low blood sugar.
Tell your doctor right away if you are pregnant. Pregnancy may cause or worsen diabetes. Discuss a plan with your doctor for managing your blood sugar while pregnant. Your doctor may change your diabetes treatment during your pregnancy (such as diet and medications including insulin).
Insulin Isophane and regular passes into breast milk but is unlikely to harm a nursing infant. Consult your doctor before breastfeeding. Your insulin needs may change while breastfeeding.
Different brands of this medication have different storage needs. Check the product package for instructions on how to store your brand, or ask your pharmacist. Protect insulin from light and heat. Do not store in the bathroom. Do not freeze, and do not use the insulin that has been frozen. Throw away all insulin products after the expiration date on the package, or after the specified number of days after it has been opened or kept at room temperature, whichever date is earlier. Keep all medications away from children and pets.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.
Some products that may interact with this drug include repaglinide, rosiglitazone.
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