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Dextroamphetamine Sulfate



About Dextroamphetamine Sulfate

Dextroamphetamine er (Zenzedi Generic) is used to treat attention deficit hyperactivity disorder – ADHD. Dexedrine vs Adderall works by changing the amounts of certain natural substances in the brain. Dexedrine for ADHD belongs to a class of drugs known as stimulants. It can help increase your ability to pay attention, stay focused on an activity, and control behavior problems. It may also help you to organize your tasks and improve listening skills.

This medication is also used to treat a certain sleeping disorder (narcolepsy) to help you stay awake during the day. It should not be used to treat tiredness or to hold off sleep in people who do not have a sleep disorder.

How to use

Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start taking Dextroamphetamine er (Zenzedi Generic) and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

  • Take Dexedrine for ADHD with or without food as directed by your doctor.
  • Usually 1 to 3 times a day.
  • The first dose is usually taken when you wake up in the morning.
  • If more doses are prescribed, take them as directed by your doctor, usually 4-6 hours apart.
  • Taking this medication late in the day may cause trouble sleeping (insomnia).
  • If you are using the liquid form of this medication, carefully measure the dose using a special measuring device/spoon.
  • Do not use a household spoon because you may not get the correct dose.

Dexedrine vs Adderall dosage is based on your medical condition and response to treatment. Your doctor may adjust your dose to find the dose that is best for you. Follow your doctor’s instructions carefully.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.

During treatment, your doctor may occasionally recommend stopping the medication for a short time to see whether there are any changes in your behavior and whether the medication is still needed.

Don’t stop abruptly

If you suddenly stop using Dextroamphetamine er (Zenzedi Generic), you may have withdrawal symptoms (such as severe tiredness, sleep problems, mental/mood changes such as depression). To help prevent withdrawal, your doctor may lower your dose slowly. Withdrawal is more likely if you have used dextroamphetamine for a long time or in high doses. Tell your doctor or pharmacist right away if you have withdrawal.

Though it helps many people, Dexedrine vs Adderall may sometimes cause addiction. This risk may be higher if you have a substance use disorder (such as overuse of or addiction to drugs/alcohol). Do not increase your dose, take it more often, or use it for a longer time than prescribed. Properly stop the medication when so directed.

When Dextroamphetamine er (Zenzedi Generic) is used for a long time, it may not work as well. Talk with your doctor if this medication stops working well.

Tell your doctor if your condition does not improve or if it worsens.

Side effects

  • Nausea
  • stomach upset
  • cramps
  • loss of appetite
  • diarrhea
  • dry mouth
  • headache
  • nervousness
  • dizziness
  • trouble sleeping
  • sweating
  • weight loss
  • irritability
  • restlessness

If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using Dexedrine vs Adderall do not have serious side effects.

This medication may raise your blood pressure. Check your blood pressure regularly and tell your doctor if the results are high.

Tell your doctor right away if you have any side effects, including signs of blood flow problems in the fingers or toes (such as coldness, numbness, pain, or skin color changes), unusual wounds on the fingers or toes, mental/mood/behavior changes (such as agitation, aggression, mood swings, depression, hallucinations, abnormal thoughts/behavior, thoughts of suicide), uncontrolled movements, muscle twitching/shaking, outbursts of words/sounds, change in sexual ability/interest, swelling ankles/feet, extreme tiredness, significant unexplained weight loss, frequent/prolonged erections (in males).

Some serious and rare side effects

Get medical help right away if you have any very serious side effects, including

  • shortness of breath
  • chest/jaw/left arm pain
  • severe headache
  • fainting
  • fast/pounding/irregular heartbeat
  • seizures
  • weakness on one side of the body
  • slurred speech
  • confusion
  • blurred vision

Dexedrine vs Adderall may increase serotonin and rarely cause a very serious condition called serotonin syndrome/toxicity. The risk increases if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take (see Drug Interactions section). Get medical help right away if you develop some of the following symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, severe nausea/vomiting/diarrhea, twitching muscles, unexplained fever, unusual agitation/restlessness.

A very serious allergic reaction to Dexedrine vs Adderall is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction.

Warnings & Precautions

  1. Before taking Dextroamphetamine er (Zenzedi Generic), tell your doctor or pharmacist if you are allergic to it.
  2. Before using Dexedrine for ADHD, tell your doctor or pharmacist your medical history.
  3. Do not drive, use machinery, or do anything that needs alertness until you can do it safely.
  4. Limit alcoholic beverages.
  5. Before having surgery, tell your doctor or dentist about all the products you use.

Children may be more sensitive to the side effects of this drug, especially weight loss. Dexedrine for ADHD may slow down a child’s growth. The doctor may recommend temporarily stopping the medication from time to time to reduce this risk. Monitor your child’s weight and height. Consult your doctor or pharmacist for more details.

Older adults may be more sensitive to the side effects of this drug, especially chest pain, trouble sleeping, or weight loss.

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. Infants born to mothers who are dependent on this medication may be born too soon (premature) and have low birth weight. They may also have withdrawal symptoms. Tell your doctor right away if you notice possible mood changes, agitation, or unusual tiredness in your newborn.

Dexedrine for ADHD passes into breast milk and may have undesirable effects on a nursing infant. Therefore, breastfeeding is not recommended while using this drug. Consult your doctor before breastfeeding.


Store Zenzedi at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Drug interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

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5 mg, 10 mg, 15 mg, 20 mg, 30 mg



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