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About Tretinoin

Tretinoin Obagi is used to treat acne. Refissa cream may decrease the number and severity of acne pimples and promote quick healing of pimples that do develop. Tretinoin cream for acne belongs to a class of medications called retinoids. Refissa for sale online works by affecting the growth of skin cells.

How to use

Read the Patient Information Leaflet if one is available from your pharmacist. Consult your doctor or pharmacist if you have questions.

  • Wash your hands before applying Tretinoin Obagi.
  • Gently clean the affected skin with a mild or soapless cleanser and pat dry.
  • Use your fingertips to apply a small amount of medication in a thin layer, usually once daily at bedtime or as directed by your doctor.
  • A gauze pad or cotton swab can be used to apply the liquid.
  • For some preparations, you should wait 20-30 minutes after cleaning your face before applying Tretinoin cream for acne.
  • Consult the label directions, the Patient Information Leaflet, or your pharmacist if you have any questions.
  • Use this medication on the skin only.
  • Do not apply to the inner lip area or inside the nose/mouth.
  • Do not apply to cut, scraped, sunburned, or eczema-affected skin.

Avoid getting Refissa for sale online in your eyes. If this medication gets into your eyes, flush with large amounts of water. Call your doctor if eye irritation develops. Wash your hands after using the medication to avoid accidentally getting it in your eyes.

Dosage and treatment

During the first few weeks of using Tretinoin cream for acne, your acne might appear worse because the medication is working on pimples forming inside the skin. It may take up to 8-12 weeks to notice results from Refissa for sale online.

Use Tretinoin Obagi regularly in order to get the most benefit from it. To help you remember, use it at the same time each day. Do not use a larger amount or use it more frequently than recommended. Your skin will not improve any faster, and it will increase the risk of developing redness, peeling, and pain.

Refissa cream is available in different strengths and forms (e.g., gel, cream, solution). The best type of medication for you to use will depend on the condition of your skin and your response to therapy. Inform your doctor if your condition persists or worsens.

Side effects

A brief sensation of warmth or stinging may occur immediately after applying the medication. Skin redness, dryness, itching, scaling, mild burning, or worsening of acne may occur during the first 2-4 weeks of using the medication. These effects usually decrease with continued use. A daytime moisturizer may be helpful for excessive dry skin (see Notes).

If any of these Tretinoin cream for acne effects persist or worsen, notify your doctor or pharmacist promptly. Your doctor may want you to decrease how often you use tretinoin, change the strength or type, or have you stop using it.

Remember that your doctor has prescribed Refissa cream because he or she has judged that your benefit is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if you experience: blistering, crusting, severe burning/swelling of the skin, eye redness and watering (conjunctivitis), eyelid swelling, skin discoloration.

A very serious allergic reaction to Tretinoin Obagi is unlikely, but seek immediate medical attention if it occurs.

Warnings & Precautions

  1. Before using Tretinoin Obagi, tell your doctor or pharmacist if you are allergic to it.
  2. Before using Refissa cream, tell your doctor or pharmacist your medical history.
  3. Limit your time in the sun.
  4. Avoid tanning booths and sunlamps.

Avoid electrolysis, waxing, and chemical depilatories for hair removal on the treated areas while using this product.

If you have recently used products containing sulfur, resorcinol, or salicylic acid, use tretinoin with caution. Wait until the effects of such products on the skin have decreased before using Tretinoin cream for acne.

During pregnancy, Refissa for sale online should be used only when clearly needed. It may harm an unborn baby. Discuss the risks and benefits with your doctor.

It is not known whether Refissa for sale online passes into breast milk. Consult your doctor before breastfeeding.


Emporium at room temperature away from light and moisture. Gel preparations are flammable. Do not expose to heat or fire sources. Do not smoke during use. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

Drug interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.



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